1170 adult patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia (Ph+ ALL) undergoing alloPBSCT
Anti-thymocyte globulin (ATG)
In a multivariate model, the use of ATG was associated with reduced risk of overall chronic GVHD and extensive chronic GVHD. It was also associated with better GRFS, despite increased risk of relapse. No significant effect was found with regard to the risk of non-relapse mortality and overall mortality.